Home Back

Henderson-Hasselbalch Equation Calculator

1. What is a Henderson-Hasselbalch Calculator?

Definition: This calculator uses the Henderson-Hasselbalch equation to determine the pH of a buffer solution based on the concentrations of the conjugate base [A⁻], the acid [HA], and the acid dissociation constant (Kₐ).

Purpose: It is widely used in chemistry and biology to predict the pH of buffer systems, aiding in the preparation of solutions with specific pH values.

2. How Does the Calculator Work?

The calculator applies the Henderson-Hasselbalch equation:

\[ \text{pH} = \text{pKₐ} + \log_{10} \left( \frac{[\text{A⁻}]}{[\text{HA}]} \right) \]

Explanation: Enter the conjugate base concentration (e.g., 0.1 M), acid concentration (e.g., 0.1 M), and Kₐ (e.g., 1.8 × 10⁻⁵ for acetic acid). The calculator computes pKₐ from Kₐ and calculates the pH.

3. Importance of the Henderson-Hasselbalch Equation

Details: This equation is essential for understanding buffer capacity and maintaining stable pH levels in chemical reactions, biological systems, and pharmaceutical formulations.

4. Using the Calculator

Tips: Input the concentrations of [A⁻] and [HA] with their units (e.g., M, mM), and the Kₐ value. Ensure Kₐ is positive and concentrations are valid to avoid calculation errors.

Henderson-Hasselbalch Calculator© - All Rights Reserved 2025